The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via σ 1 receptor activation: comparison with the effects of dextromethorphan
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منابع مشابه
The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan.
In a previous study, we demonstrated that a dextromethorphan analog, dimemorfan, has neuroprotective effects. Dextromethorphan and dimemorfan are high-affinity ligands at sigma1 receptors. Dextromethorphan has moderate affinities for phencyclidine sites, while dimemorfan has very low affinities for such sites, suggesting that these sites are not essential for the anticonvulsant actions of dimem...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2005
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0705998